Genprex Announces Groundbreaking Gene Therapy to Treat Type 1 Diabetes

Genprex Announces Groundbreaking Gene Therapy to Treat Type 1 Diabetes

Previously Published on Genprex.comย โ€”ย Genprex, Inc.ย (โ€œGenprexโ€ or the โ€œCompanyโ€) , aย clinical-stage gene therapy company focused on developing life-changing therapies for patients with cancer and diabetes, today announced that data highlighting the potential of Genprexโ€™s gene therapy for Type 1 diabetes is being presented by its research collaborators at the University of Pittsburgh (Pitt)ย at the 16th International Conference on Advanced Technologies & Treatments for Diabetes (ATTD 2023) taking place February 22-25, 2023 in Berlin, Germany.

Results show statistically significant decreases in insulin requirements, increases in c-peptide levels and improvements in glucose tolerance compared to baseline. –ย Disruptive gene therapy approach developed by University of Pittsburgh researchers may be a promising treatment for Type 1 and Type 2 diabetes.

Abstract data

The abstract data were released, and the presentation will be delivered on February 25th at 2:25 pm CET by Ranjeet S. Kalsi, DO, a member of the laboratory of George Gittes, MD, from Pittโ€™s Division of Pediatric Surgery, Pittsburgh, Pennsylvania. The complete presentation will be available on the Companyโ€™s websiteย hereย following the close of Dr. Kalsiโ€™s presentation.

The presentation titled, โ€œPancreatic Intraductal Infusion of Adeno-Associated Virus (AAV) to Treat Non-Human Primates in a Toxin-Induced Diabetes Model,โ€ will report results from eight non-human primates (NHPs) with toxin-induced diabetes after streptozocin administration. They received aย novel infusion process that used an AAV vector to deliver Pdx1 and MafA genes directly to the pancreas.

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